Printemps de la Cardiologie
Recherche Fondamentale & Clinique

6 et 7 avril 2017
Nantes
La Cité - Centre des Congrès

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Programme en cours

Programme

6 Avril 2017


08:30 - 09:00
Séance plénière
Ouverture du Congrès
Auditorium 450
Stéphane Germain, Paris - Président du GRRC
Jean-Yves Le Heuzey, Paris - Président de la SFC
Vincent Probst, Nantes - Co-Président du Congrès
Vincent Sauzeau, Nantes - Co-Président du Congrès
Pascale Jolliet, Nantes - Doyen de la Faculté de Médecine de Nantes
   
09:00 - 09:30
Conférence GRRC
 
Auditorium 450
Stéphane Germain, Paris
   
 

Les étapes du développement du TAVI, état actuel et perspectives

Alain Cribier, Rouen
09:45 - 11:15
Table ronde
Progrès dans la fibrillation atriale : qui a apporté le plus ?Rythmologie
Salle 300
Dominique Babuty, Tours
Olivier Bernus, Pessac
   
 

Le point de vue du chercheur

Stéphane Hatem, Paris
 

Le point de vue du clinicien

Raphaël Martins, Rennes
 

Rôle du remodelage épicardique dans la fibrillation atriale chez le murin.

 

Rotor in atrial fibrillation and impact of ablation

09:45 - 11:15
Table ronde
Signalisation vasculaireVaisseaux
Salle 150
Laurent Loufrani, Angers
Vincent Sauzeau, Nantes
   
 

Perméabilité vasculaire et angiogenèse

Julie Gavard, Nantes
 

Benefit of Mineralocorticoid Receptor Antagonism in Acute Kidney Injury: Role of Vascular Smooth Muscle Rac1

 

Regulation of Pulmonary Vascular PW1+ Progenitor Cells Recruitment during Early Chronic Hypoxia-Induced Vessel Neomuscularization

 

Neutrophil and Thrombospondin-1 implications in flow-mediated remodeling in the microcirculation.

 

TRPV4-induced structural changes in the adventitia of intrapulmonary artery.

09:45 - 11:15
Table ronde
Le couplage excitation-contraction : nouvelles cibles thérapeutiquesInsuffisance Cardiaque
Salle 200
Hervé Le Marec, Nantes
Grégoire Vandecasteele, Châtenay-Malabry
   
 

Le récepteur de la ryanodine : acteur central de la dysfonction du myocarde ?

Alain Lacampagne, Montpellier
 

Canaux TRP dans le contrôle de l'excitation

Romain Guinamard, Caen
 

Remodelling of intracellular Ca2+ uptake in cardiac Purkinje cells; a possible origin for the triggers of ventricular tachycardias associated with myocardial ischemia.

 

High arrhythmogenic potential of calcium waves in rat isolated pulmonary vein cardiomyocytes

 

C-TERMINAL PHOSPHORYLATION OF NaV1.5 CHANNELS IMPAIRS FGF13-DEPENDENT INACTIVATION: POTENTIAL IMPACT IN HEART FAILURE

09:45 - 11:15
Table ronde
Oxygène : ami ou ennemi ?Médecine Expérimentale
Salle GH
Elise Belaidi-Corsat, Grenoble
Renaud Tissier, Maisons-Alfort
   
 

Tension en oxygène et cellules souches mésenchymateuses : clef de la médecine régénérative ?

Hervé Petite, Paris
 

Tension en oxygène et phénotype inflammatoire des cellules en culture

Roberto Motterlini, Créteil
 

EPAC1-MEDIATED ER-MITOCHONDRIA INTERACTIONS PROMOTE DELETERIOUS Ca2+ UPTAKE AND CELL DEATH DURING ISCHEMIA/REPERFUSION INJURY.

 

Opposite effects of mitochondrial fusion and fission deficiencies in the context of myocardial ischemia-reperfusion 

 

LE SECRETOME DES FIBROBLASTES CARDIAQUES MODULE LA REPONSE IMMUNITAIRE ET LA SURVIE DES CARDIOMYOCYTES EN SITUATION D’ISCHEMIE-REPERFUSION. 

09:45 - 11:15
Table ronde
Valvulopathies aortiques de l'adulte : quelles prises en charge ?Transversal
Salle I
Claire Bouleti, Paris
Martine Gilard, Brest
   
 

Chirurgie : quand peut-on conserver la valve aortique ?

Daniel Grinberg, Lyon
 

La nouvelle génération de valves TAVI résout-elle tous les problèmes ?

Hélène Eltchaninoff, Rouen
 

Relationship between Proximal Aorta Morphology and  Progression Rate of Aortic Stenosis

 

Perioperative complications in transcathter aortic valve implantation, in patients with pre existing atrial fibrillation : vitamine K antagonist treatment versus new direct oral anticoagulant

 

Thoracic aorta calcifications and TAVI : evaluation of automatic measurements and prognostic value on the cohort of Rouen.

11:15 - 11:45
Pause-café - Visite de l'exposition
 
   
11:45 - 13:00
Table ronde
The beat goes on !Rythmologie
Salle 300
Charles Guenancia, Dijon
Raphaël Martins, Rennes
   
 

L'automatisme cardiaque

Flavien Charpentier, Nantes
 

Une ou plusieurs cellules atriales ?

Fabien Brette, Bordeaux
 

De novo and familial Connexin45 Mutant R75H Causes Progressive Atrioventricular Block Associated with Craniofacial and Dentodigital Dysmorphisms

 

Diagnosis accuracy of provocative tests in concealed Long QT Syndrome.

 

Shall we implant a pacemaker only in case of complete atrioventricular block following TAVI ? Quantification of ventricular pacing rate according to pacemaker indication

11:45 - 13:00
Session d'experts

Session commune avec la Nouvelle Société Française d'Athérosclérose

Les nouvelles fonctions de l'athéroscléroseVaisseaux
Salle 150
Michel Krempf, Nantes
Gilles Lemesle, Lille
   
 

Métabolisme du système hématopoïétique et immunitaire dans les pathologies cardiovasculaires

Laurent Yvan-Charvet, Nice
 

Inflammation et athérosclérose

Soraya Taleb, Paris
 

L’endothelium : une cible particulière des estrogènes et de leur recepteur

Jean Francois Arnal, Toulouse
11:45 - 13:00
Table ronde
De l'hypertrophie à l'insuffisance cardiaqueInsuffisance Cardiaque
Salle 200
Mathias Mericskay, Paris
Jane-Lise Samuel, Paris
   
 

Rôle du STIM1 dans l'hypertrophie cardiaque adaptaptive

Jean-Sébastien Hulot, Paris
 

Voie Wnt : une clé dans la transition vers l'insuffisance cardiaque

Cécile Duplàa, Bordeaux
 

Cardioprotective effect of Orai1 inhibition against pressure overload-induced pathological remodeling

 

From heart development to cardiac regeneration: role of the Fibroblast Growth Factor FGF10

 

Role of cardiac fibroblast AMPKα1 in left ventricular remodeling after myocardial infarction 

11:45 - 13:00
Session d'experts
Exosomes : acteurs et biomarqueursMédecine Expérimentale
Salle GH
Chantal Boulanger, Paris
Nathalie Rosenblatt-Velin, Lausanne
   
 

Rôle de l'exosome dans la cardioprotection

Chantal Boulanger, Paris
 

Contrôle de la fonction endothéliale par les microvésicules circulantes

Ramaroson Andriantsitohaina, Angers
 

Fonction des exosomes dans les thérapies cellulaires

Nisa-Karin Renault, Paris
11:45 - 13:00
Atelier thématique
Présenter sa recherche : un travail à part entièreTransversal
Salle I
Yves Juilliere, Nancy
Xavier Prieur, Nantes
   
 

Comment faire une bonne présentation orale : trucs et astuces

Nicolas Danchin, Paris
 

L'art et la manière de faire son powerpoint

Denis Angoulvant, Tours
13:15 - 14:15
Déjeuner-Débat

MSD France

La lettre de sortie chez un patient en post SCA : traduire les données des études dans la pratiqueVaisseaux
Salle 150
Martine Gilard, Brest
Michel Krempf, Nantes
   
 

Choix et objectifs du traitement ciblant le LDL

Vincent Probst, Nantes
 

Choix et durée du traitement anti-thrombotique

Etienne Puymirat, Paris
13:15 - 14:15
Déjeuner-Débat

Novartis

Prise en charge de l’insuffisance cardiaque en pratique clinique en 2017Insuffisance Cardiaque
Salle 200
Jean-Noël Trochu, Nantes
   
 

Place des Biomarqueurs dans l’Insuffisance cardiaque en 2017

Christophe Meune, Bobigny
 

Au-delà des études : quels enseignements nous apportent les cohortes? (Real Word evidence)

François Picard, Bordeaux
 

Table ronde

Christophe Meune, Bobigny - François Picard, Bordeaux - Jean-Noël Trochu, Nantes
13:15 - 14:15
Déjeuner-Débat

AstraZeneca

Recherche clinique sur la maladie coronaire : une ambition françaiseMédecine Expérimentale
Salle GH
Denis Angoulvant, Tours
Gilles Lemesle, Lille
   
 

L'odyssée FAST-MI

Nicolas Danchin, Paris
 

Animer la recherche au niveau national: le réseau FACT

Tabassome Simon, Paris
14:15 - 14:45
Pause-café - Visite de l'exposition
 
   
14:45 - 15:45
Séance plénière
Recherche translationnelle : Médecine 2.0
Auditorium 450
Stéphane Germain, Paris
Jean-Yves Le Heuzey, Paris
   
 

Introducation sur les Big data

Richard Redon, Nantes
 

Big data des cliniciens

Anita Burgun, Paris
 

Que faire de ces informations ? Sécurité, éthique

Frédérique Claudot, Nancy
16:00 - 17:15
Atelier
La rythmologie en s'amusantRythmologie
Salle 300
Christophe Leclercq, Rennes
Cyril Zakine, Marne-la-Vallée
   
 

L'ECG : la vérité se trouve entre les lignes

Nachwan Ghanem, Eaubonne
 

Cas cliniques et quizz en rythmologie

Rodrigue Garcia, Poitiers
16:00 - 17:15
Table ronde
Vaisseaux et système nerveux centralVaisseaux
Salle 150
Hubert Desal, Nantes
Alain Furber, Angers
   
 

Matrisome et maladies des petits vaisseaux cérébraux 

Anne Joutel, Paris
 

Nouvelles avancées dans les anévrysmes intracrâniens

Gervaise Loirand, Nantes
 

Endothelial depletions of ROR2 and PDZRN3 in mice attenuate Blood Brain Barrier (BBB) disruption in a model of focal cerebral stroke

 

Lysyl oxidase like-2 (LOXL2) regulates endothelial mechanotransduction and 3D vascular morphogenesis through scaffolding of basement membrane  

 

Context-dependent regulation of capillary morphogenesis by angiopoietin-like 4

16:00 - 17:15
Session d'experts
L'insuffisance cardiaque à fraction d'éjection préservée (FE) :
un challenge pour la recherche translationnelleInsuffisance Cardiaque
Salle 200
Loïc Bière, Angers
Jean-Noël Trochu, Nantes
   
 

Quid de l'insuffisance cardiaque à FE préservée chez l'homme

Jean-Jacques Mercadier, Châtenay-Malabry
 

Pertinence des modèles animaux dans l'insuffisance cardiaque à FE préservée

Bijan Ghaleh, Créteil
 

Bases moléculaires spécifiques de l'insuffisance cardiaque à FE préservée : mythe ou réalité ?

Chantal Gauthier, Nantes
16:00 - 17:15
Table ronde
Après la cardioprotection : what else ?Médecine Expérimentale
Stéphane Germain, Paris
Fabrice Prunier, Angers
   
 

La circulation coronaire : cible de la cardioprotection

David Garcia-Dorado, Barcelone - Espagne
 

La circulation lymphatique cardiaque : importance en cardioprotection

Ebba Brakenhielm, Rouen
 

Apelin is involved in the maintenance of lymphatic barrier integrity in ischemic heart disease

 

The Brain Natriuretic Peptide Improves Cardiac Function After Myocardial Infarction Through Vascular Regeneration

 

Cyclophilin D is a regulator of NLRP3 inflammasome.

16:00 - 17:15
Session d'experts
La théorie du genre : une réalité en cardiovasculaire ?Transversal
Salle I
Luc Bertrand, Bruxelles
Jane-Lise Samuel, Paris
   
 

Différences de prise en charge dans l'infarctus du myocarde

Stéphane Manzo-Silberman, Paris
 

Spécificités de la physiopathologie cardiaque selon le sexe

Renée Ventura-Clapier, Châtenay-Malabry
 

Quinze ans après la Women Health Initiative : où en est t-on de la relation oestrogènes - athérome ?

Jean Francois Arnal, Toulouse
17:15 - 19:00
Session de Posters Commentés & Visite de l'exposition
 
   
17:15 - 19:00
Poster
1 - Inflammation
Jean Francois Arnal, Toulouse
Gilles Lemesle, Lille
   
 

Inflammatory macrophages play a protective role in compensated cardiac hypertrophy induced by chronic adrenergic stimulation

Mathilde Flamant, Paris
 

Implication of the Neutrophil Gelatinase-Associated Lipocalin (NGAL) from immune cells in aldosterone induced cardiovascular remodeling

 

Mathieu Buonafine, Paris
 

MicroRNA 21 and Hypoxia Inducible Factor 1 coordinate the impact of B lymphocytes on cardiac function after acute myocardial infarction

Cristina Pinto, Paris
 

Endotoxemia induces production of LTB4, neutrophil infiltration and collagenolysis in atherosclerotic plaques.

Marie-Anne Mawhin, Paris
 

nmMLCK is essential to trigger endothelial dysfunction, interleukin-6 secretion and endothelial permeability in an experimental model of intermittent hypoxia

Sylvain Recoquillon, Angers
 

Peri-procedural serum fibrinogen and CRP elevation before Percutaneous Coronary Intervention significantly predict stent thrombosis and Major Cardiovascular ischemic Events at 15-months

Denis Angoulvant, Tours
 

Le Chlorure de Sodium altère la polarisation des Cellules Dendritiques en lymphocytes TH1.

Sally Al-Hajj, Tours
 

Effects of low doses of esmolol on cardiac and vascular function in experimental septic shock

Chaojie Wei, Nancy
 

Role of indoleamine 2,3 dioxygenase in abdominal aortic aneurysm development 

Sarvenaz Metghalchi, Paris
 

Characterisation of Endogenous Cardiac Inflammatory Cells displaying a Cardiogenic Potential.

Nathalie Rosenblatt-Velin, Lausanne
 

PI3Kgamma a novel therapeutic target to increase reendothelialization in mice through modulation of CXCL10 secretion

 

The Endothelin B Receptor Plays a Crucial Role for the Recruitment of Neutrophils to the Endothelium in Sickle Cell Disease

Pierre-Louis Tharaux, Paris
17:15 - 19:00
Poster
2 - Athérosclérose, thrombose, hémostase
Patrick Lacolley, Nancy
Pierre-Louis Tharaux, Paris
   
 

PROGNOSTIC IMPACT OF BODY MASS INDEX ON INTRA-HOSPITAL BLEEDING COMPLICATIONS AFTER ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION

Delphine Ingremeau, Paris
 

Platelet function and microparticle levels in atrial fibrillation: Changes during the acute episode

Line Pourtau, Bordeaux
 

Quality of management of oral anticoagulation in elderly and younger patients

 

 

Génération de thrombine à la surface des cellules musculaires lisses vasculaires dans les anévrismes aortiques.

 

Mélusine Didelot, Nancy
 

Role of Wnt5a signaling in cholesterol homeostasis and prevention of atherosclerosis

Sara Awan, Strasbourg
 

Apple procyanidins decrease oxidation of dietary lipids in the in vitro digestion of a Western meal

Gaetan Bolea, Avignon
 

Contrôle de la génération de thrombine plaquette-dépendante par Arhgef1, le facteur d’échange de la petite protéine G RhoA 

Camille Rouillon, Nancy
 

Targeting the cysteinyl-leukotriene pathway: a new treatment paradigm for obstructive sleep apnea precision medicine?

Claire Arnaud, Grenoble
 

ABCC6 dysfunction in the rare disease pseudoxanthoma elasticum is associated to increased platelet activation and prothrombotic state.

Gilles Kauffenstein, Angers
 

Simplifying the Assessment of Coronary Artery Stenosis by Enhancing Instantaneous Wave Free Ratio.

Vincent Spagnoli, Paris
17:15 - 19:00
Poster
3 - Ischémie reperfusion, SCA, AVC
Stéphane Germain, Paris
Renaud Tissier, Maisons-Alfort
   
 

L'utilisation des scores modernes dans l’évaluation du risque individuel de la double anti agrégation plaquettaire prolongée pourrait modifier la durée de cette bithérapie chez les patients SCA ST+

Cécile Caze, La Chaussée St Victor
 

LE SECRETOME DES FIBROBLASTES CARDIAQUES MODULE LA REPONSE IMMUNITAIRE ET LA SURVIE DES CARDIOMYOCYTES EN SITUATION D’ISCHEMIE-REPERFUSION. 

Claudie Lefort, Tours
 

New biomarker ST2: predictor of early complications in acute coronary syndromes ?

Mouna Ben Kilani, Tunis
 

Prognosis of very elderly patients with non-ST-elevation acute coronary syndrome: a comparison between initial coronary angiography and medical treatment

Pauline Becat, Seignosse
 

Bioresorbable Vascular Scaffold compared to conventional drug eluting stent in ST-elevation myocardial infarction: mid-term outcomes

 

Myocardial protection from ischemia/reperfusion injury by exogenous galanin fragment

Andrei Timotin, Toulouse
 

Fermeture percutanée de l’appendice auriculaire  gauche par le dispositif Watchmann  : expérience monocentrique de cinquante-neuf (59) patients.

Aliou Diallo, Jossigny
 

Cardioprotective effects of chinese medicine NurAiD™II

Stephanie Barrere-Lemaire, Montpellier
 

Mitochondrial cyclophilin D-dependent effects of therapeutic hypothermia in post-cardiac arrest syndrome

Vincent Jahandiez, Lyon
 

Cyclophilin D is a regulator of NLRP3 inflammasome.

Alexandre Paccalet, Bron
 

Has Re-elevation of ST segment after an Acute Myocardial Infarction a Prognostic Significance ?

Léo Cuenin, Lyon
17:15 - 19:00
Poster
4 - Ischémie reperfusion, SCA, AVC
Claire Arnaud, Grenoble
Frank Lezoualc'h, Toulouse
   
 

SIRT3-dependent ischemic post-conditioning fails at reducing infarct size in old mice

Camille Villedieu, Lyon
 

Etude du rôle cardioprotecteur des canaux TRPV1 dans la lignée cellulaire H9C2

Nolwenn Tessier, Lyon
 

Galectin-3 inhibition prevents cardiac dysfunction in murine experimental type 3 Cardio-Renal Syndrome

Mathilde Prud'homme, Le Pecq
 

Myocardial contractile function and vulnerability to ischemia ex vivo can be worsened by prior experimental ischemic stroke in rats

Alexandre Méloux, Dijon
 

Influence of hyponatremia on short-/long-term outcomes in older patients with acute myocardial infarction

 

Kaoutar Kharbouche, Casablanca
 

Does left ventricular ejection fraction impact on the outcome of patients affected by chronic total occlusions and undergoing percutaneous revascularization attempts? 

Marouane Boukhris, Ariana
 

La stimulation de P2Y11R réduit les lésions de reperfusion dans une lignée de cardiomyocytes humains et améliore la survie du greffon dans un modèle murin d'allogreffe cardiaque hétérotopique

Lauriane Benoist, Tours
 

Safety of Morphine in anterior acute ST-segment elevation myocardial infarction (STEMI).

Mickael Bonin, Nantes
 

Cardiac mGluR1 metabotropic receptors protect against ischemia-reperfusion injury in the mouse heart

Anne Vincent, Montpellier
 

Early coronary reperfusion improves cardiovascular outcome after extracorporeal resuscitation in pigs

Alice Hutin, Paris
 

Cardioprotective effect of opioids in an experimental model of ischemia-reperfusion injuries

Laurent Coulbault, Caen
17:15 - 19:00
Poster
5 - Mitochondries et métabolisme
Jérémy Fauconnier, Montpellier
Anne Lombes, Paris
   
 

Mitochondrial biogenesis is driven by protein translation during ischemia and reperfusion

Amandine Thomas, Los Angeles
 

Mitochondrial dysfunctions and signaling pathways upon glucose variability: an in vitro study on the HL-1 cardiac cell line.

Patrick Mordel, Caen
 

Metabolism and acetylation contribute to leucine-mediated inhibition of cardiac glucose uptake

Edith Renguet, Bruxelles
 

EPAC1-CaMKII pathway targets mitochondrial IDH2 during cardiac ischemia

Marion Laudette, Toulouse
 

Alternative NAD+ biosynthesic pathways activated by energy stress in cardiac cells

Robin Deloux, Châtenay-Malabry
 

Non metabolic and metabolic effects of cardiac specific AMPKalpha2 deficiency.

Lucile Grimbert, Châtenay-Malabry
 

AMPK acts via OGT and GFAT to regulate O-GlcNAcylation during cardiac hypertrophy development

Florence Mailleux, Bruxelles
 

Metabolic therapy: cobalamin and folate protect mitochondrial oxidative capacity and contractile function in myocardial dysfunction

Jérôme Piquereau, Châtenay-Malabry
17:15 - 19:00
Poster
6 - Mitochondries et métabolisme
Luc Bertrand, Bruxelles
David Montaigne, Lille
   
 

Aldosterone and mitochondrial dysfunction in human atrial cardiomyocytes

Pierre Ollitrault, Caen
 

Calcium ionophores for the investigation of mitochondrial permeability transition pore opening in murine cardiac myocytes.

Mathieu Panel, Créteil
 

cardiac characterization of a heterozygous mouse model deficient in Drp1

Rima Kamel, Angers
 

Phosphodiesterase type 2 localized in cardiac mitochondria regulates mitochondrial membrane potential, swelling and calcium accumulation

Dawei Liu, Châtenay-Malabry
 

Metabolism of omega 3 : which is in charge of cardioprotective effect ?

 

Two weeks high fat diet is associated with altered SR Ca2+ homeostasis and early mitochondrial defects

Mathilde Lacote, Montpellier
 

Cardiac mitochondrial complex I dysfunction is associated with an increase in sarcoplasmic reticulum leak in a Duchenne muscular dystrophy. 

Claire Angebault-Prouteau, Montpellier
 

Evidence for a contribution of mitochondrial permeability transition pore opening to ventricular arrhythmia maintenance

Philippe Pasdois, Bordeaux
 

Early metabolic and mitochondrial remodeling in a pig model of atrial fibrillation

Philippe Pasdois, Bordeaux
17:15 - 19:00
Poster
7 - Angiogenèse et microcirculation
Nathalie Rosenblatt-Velin, Lausanne
Chantal Boulanger, Paris
   
 

Endothelial cell dysfunction is a new potential therapeutic target for the treatment of critical limb ischemia

Marie-Ange Renault, Bordeaux
 

Thioredoxin interacting protein endothelial deletion protects from alterations of angiogenic process in adult mice submitted to vascular accelerated aging

Alison Domingues, Paris
 

Development of an in vitro vascularised dermal substitute to study angiogenesis

Adele Mauroux, Paris
 

Context-dependent regulation of capillary morphogenesis by angiopoietin-like 4

Athanasia Liabotis, Paris
 

In vitro and in vivo antiangiogenic properties of Phostine 3.1a as a potential pharmacological compound to fight against diseases with excess vascularization

Simon Bousseau, Nantes
 

Lysyl oxidase like-2 (LOXL2) regulates endothelial mechanotransduction and 3D vascular morphogenesis through scaffolding of basement membrane  

Marion Marchand, Paris
 

Perivascular recruitment of mesenchymal stem cells in vascularized 3D hydrogel

Yoann Atlas, Paris
 

Endothelial ATG5 is required for endothelial flow sensing and angiogenesis 

Olivia Lenoir, Paris
 

Endothelial Connexin40 regulates vascular sprouting and maturation during developmental retinal angiogenesis

Florian Alonso, Bordeaux
 

Abrogating Frizzled7 in endothelial cell protects against the development of pathological angiogenesis during proliferative retinopathy

Marie-Lise Bats, Bordeaux
 

Evaluation of regenerative potential of extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) in murine model of hind limb ischemia

Luisa Vergori, Angers
17:15 - 19:00
Poster
8 - Electrophysiologie
Stéphane Hatem, Paris
Raphaël Martins, Rennes
   
 

Shall we implant a pacemaker only in case of complete atrioventricular block following TAVI ? Quantification of ventricular pacing rate according to pacemaker indication

Adrian Mirolo, Rouen
 

The role of mechanosensitive ion channels during zebrafish heart development and regeneration

Nathalie Nasr, Montpellier
 

Caractéristiques et suivi des patients de plus de 80 ans implantés d’un défibrillateur automatique implantable en prévention primaire 

Cyril Zakine, Marne-la-Vallée
 

Rôle du remodelage épicardique dans la fibrillation atriale chez le murin.

Pierre-Marc Lallemand, Paris
 

Is the SonRTip atrial lead reliable for a long term?   

Jean-Baptiste Moreau, Brest
 

La sensibilité du baroréflexe chez les patients porteurs d'un défibrillateur cardiaque en prévention primaire de mort subite. Etude pilote cas-témoins.

Nicolas Bidegain, Poitiers
 

Intérêt pronostique du volume et de la fraction d'éjection de l'oreillette gauche, mesurées au scanner multicoupe, sur le succès d'ablation de la fibrillation auriculaire

 

Non-invasive multimodal imaging techniques for in vivo characterization of electrical dyssynchrony in large animal models: feasibility study

Carolina Carlos Sampedrano, Bordeaux
 

Remodelling of intracellular Ca2+ uptake in cardiac Purkinje cells; a possible origin for the triggers of ventricular tachycardias associated with myocardial ischemia.

Gilles Bru-Mercier, Bordeaux
 

De novo and familial Connexin45 Mutant R75H Causes Progressive Atrioventricular Block Associated with Craniofacial and Dentodigital Dysmorphisms

Naomasa Makita, Nagasaki
17:15 - 19:00
Poster
9 - Electrophysiologie
Vincent Probst, Nantes
Jean-Jacques Schott, Nantes
   
 

Involvement of CASK protein domains in the down regulation of the sodium channel Nav1.5 in cardiomyocytes

Adeline Beuriot, Paris
 

Heart automaticity in mice lacking “pacemaker” L-type Cav1.3 and T-type Cav3.1 channels.

Matthias Baudot, Montpellier
 

Functional role of L-type Cav1.3 channels in cholinergic regulation of heart automaticity

Julien Roussel, montpellier
 

Cause of aborted cardiac arrest in patients implanted with a defibrillator in secondary prevention

Benjamin Stordeur, Poitiers
 

Concurrent genetic or pharmacologic targeting of L-type Ca2+ Cav1.3 and ‘funny’ f-(HCN) channels eliminates the ‘fight-or-flight‘ response in sino-atrial pacemaker activity

Pietro Mesirca, Montpellier
 

Role of L-type Cav1.3 Ca2+ channels in Ca2+ handling and SAN pacemaker activity altered by external conditions.

 

Contribution of Small K+ channels to Sinoatrial Node pacemaking of control and atrial-specific Na+/Ca2+ exchange knock out mice.

Angelo Giovanni Torrente, Montpellier
 

Overexpression of the cardiac Na+ channel in Scn5a deficient mice using AAVs

Nathalie Neyroud, Paris
 

Compartmentalized structure of the moderator band provides a substrate for macroreentrant ventricular tachycardia

Richard Walton, Bordeaux
 

Electrical properties of gap junction channels: dependence on the ratio of co-expressed connexins 43:40 and 43:45.

Sébastien Chaigne, Bordeaux
17:15 - 19:00
Poster
10 - Insuffisance cardiaque et cardiomyopathies + Réadaptation, exercice, prévention
Jean-Jacques Mercadier, Châtenay-Malabry
Grégoire Vandecasteele, Châtenay-Malabry
   
 

A Novel myocardial fibrosis risk score in Heart Failure with preserved ejection fraction

Amandine Secq, Rouen
 

Cardiac contractility in heart failure with preserved ejection fraction: implication of endothelium and calcium pathway.

Marine Ferron, Nantes
 

Evaluation of metabolism alteration in the development of heart failure with preserved ejection fraction. 

Marine Ferron, Nantes
 

Identification of signalling pathways potentially involved in the development of heart failure with preserved ejection fraction

Justine Dhot, Nantes
 

The impact of functional mitral valve regurgitation in 1600 patients with chronic heart Failure

 

 

Ilham El Haddad, Casablanca
 

Age-dependent decrease of Cx43 expression is implicated on ventricular fibrosis in Scn5a+/- mice

Justine Patin, Nantes
 

Finerenone improves left ventricular diastolic, coronary and cardiac mitochondrial function in post-menopausal mice

A. Gueret, Rouen
 

Inhibition of PIKfyve improves cardiometabolic phenotype in chronic diet-induced obesity through activation of SIRT3

Frédéric Boal, Toulouse
 

Is epicardial fat thickness associated with subclinical cardiac dysfunction?  

Mathilde Baudet, Paris
 

The SGLT2 inhibitor dapagliflozin prevents cardiomyopathy

in a diabetic lipodystrophic mouse model

17:15 - 19:00
Poster
11 - Insuffisance cardiaque et cardiomyopathies + Réadaptation, exercice, prévention
Loïc Bière, Angers
Thierry Le Tourneau, Nantes
   
 

Role of EPAC in the modulation of the cardiotoxicity induced by Doxorubicin

Maxance Ribeiro, Châtenay-Malabry
 

Pulsatility as modulator of acquired VWF defect in a pig model of continuous-flow ventricular assist device

Flavien Vincent, Lille
 

SIRT1 protects the heart from endoplasmic reticulum stress-induced apoptosis through eIF2α deacetylation

Julie Pires Da Silva, Châtenay-Malabry
 

From heart development to cardiac regeneration: role of the Fibroblast Growth Factor FGF10

Sandy Payan, Marseille
 

Impact de l’invalidation conditionnelle de QSOX1 dans les cardiomyocytes lors d’un stress cardiaque aigu

Céline Luc, Paris
 

Cardiovascular beneficial effects of O-GlcNAc stimulation in the septic shock: from the function to the pathways

Antoine Persello, Nantes
 

Biodegradable polymeric nanocapsules prevent cardiotoxicity of anti-trypanosomal lychnopholide.

Charlotte Farah, Bruxelles
 

Early toxicity of doxorubicin treatment on the cell surface architecture of the cardiomyocyte in adult mice

Marie Cauquil, Toulouse
 

Early detection of heart dysfunction in doxorubicine induced-cardiotoxicity in juvenile rats with Speckle tracking echocardiography

Nourdine Chakouri, Montpellier
 

Comparaison entre abord percutané et chirurgical de l'ECMO

Arthur Charbonnier, TOURS
 

State-of-the-Art of Left Ventricular Assist Device use in France: the ASSIST-ICD registry.

Vincent Galand, Rennes
17:15 - 19:00
Poster
12 - Insuffisance cardiaque et cardiomyopathies + Réadaptation, exercice, prévention
Charles Guenancia, Dijon
Sandrine Horman, Bruxelles
   
 

Kinases activation and dysregulated autophagy in heart contribute to increased Desmin phosphorylation in heart failure

Marion Bouvet, Paris
 

Comparative effects of 4 acute treatments on the electrical phenotype of Scn5a+/ΔQKP1510-1512 mice, a new model of type 3 long QT syndrome associated with dilated cardiomyopathy.

Franck Chizelle, Nantes
 

Rôles de QSOX1 lors de l’adaptation cardiaque à une surcharge de pression

Malha Sadoune, Paris
 

Cardioprotective effect of Orai1 inhibition against pressure overload-induced pathological remodeling

Fiona Bartoli, Châtenay-Malabry
 

The nicotinamide riboside kinase2 has a dual role in the heart for the deposition of laminin in the extracellular matrix and the maintenance of myocardial NAD coenzyme level during ageing

Cynthia Tannous, Paris
 

Cardiac dysfunction is the main mechanism of aggravation of exercise intolerance in homozygous sickle cell disease patients 

Stéphane Hatem, Paris
 

Kinetic of left ventricular function and mechanic during transition from rest to exercise in elite athletes.

Omar Izem, Avignon
 

Apport de l’étude de la déformation longitudinale ventriculaire dans le diagnostic précoce de la dysplasie arythmogène du ventricule droit

Sondes Smaali, Paris
 

Hypercontractile heart and delayed cardiomyopathy in mice with cardiac-specific ablation of the RIalpha subunit of cAMP-dependent protein kinase

Audrey Varin, Châtenay-Malabry
 

Prolonged exhaustive exercise induces diastolic dysfunction with preserved systolic function mediated by oxidative stress.

Olivier Cazorla, Montpellier
17:15 - 19:00
Poster
13 - Signalisation cardiaque et vasculaire, mircro ARN, protéome
Mathias Mericskay, Paris
Vincent Sauzeau, Nantes
   
 

Endothelial depletions of ROR2 and PDZRN3 in mice attenuate Blood Brain Barrier (BBB) disruption in a model of focal cerebral stroke

Florian Gueniot, Bordeaux
 

Characterization of new adenylyl cyclase 8 isoforms possibly involved in vascular smooth muscle cells trans-differentiation and pathological vascular remodeling

Benjamin Vallin, Paris
 

Implication des exosomes dans le transport et le rôle des miR-21-5p et 222-3p lors du remodelage ventriculaire gauche post-infarctus.

Henri Charrier, Lille
 

Benefit of Mineralocorticoid Receptor Antagonism in Acute Kidney Injury: Role of Vascular Smooth Muscle Rac1

Sébastian Lechner, Paris
 

Circulating miR-155, miR-145 and let-7c as diagnostic biomarkers of the coronary artery disease

 

Collagen VI deficiency: the heart of the matter

M Saunier, Paris
 

Role of cardiac fibroblast AMPKα1 in left ventricular remodeling after myocardial infarction 

Cécile Dufeys, Rixensart
 

MIR-193B-INFLAMMASOME: A POTENTIAL PATHWAY IN ADULT CARDIOMETABOLIC DYSFUNCTIONS INDUCED BY POSTNATAL OVERFEEDING AND TARGET FOR THEIR REVERSAL

C. Greco, DIJON
 

Regulation of cardiac pacemaker activity by PDE4 isoforms

Delphine Mika, Châtenay-Malabry
 

Spatiotemporal regulation of connexin43 gap junction communication in the heart

Guillaume Pidoux, Châtenay-Malabry
 

Endothelial PDZRN3, controls vascular permeability through Wnt/PCP signaling and the PKC zeta dependent polarity complex 

Thierry Couffinhal, Bordeaux
17:15 - 19:00
Poster
14 - Thérapie génique et cellulaires, cellules souches + prolifération, apoptose et microparticules
Ramaroson Andriantsitohaina, Angers
Francesca Rochais, Marseille
   
 

Development of 3D engineered heart tissue (EHT) technology for the study of cardiac contractile dysfunction

Agathe Korniat, Paris
 

Understanding the metabolism of cardiac progenitor cells: a first step towards controlling their proliferation and differentiation?

Emilie André, Bruxelles
 

Circulating microparticles: the good, the bad and the obesity?

Saloua Dimassi, Avignon
 

Oxygen concentration modulates neonatal mouse cardiomyocyte’s fate in vitro.

Anne-Charlotte Bon, Lausanne
 

Identification of selective surface markers of adult cardiac PW1+ progenitor cells (CPCs) by proteogenomics approaches

Olivier Claude, Paris
 

Détermination du rôle du gène PW1 dans le remodelage post-infarctus dans un modèle murin invalidé pour le gène PW1

Cécile Caze, La Chaussée St Victor
 

 

Gain-of-function of Nav1.5 in cardiac fibroblasts modifies proliferation, apoptosis and differentiation of these cells

Claire Castro, Nantes
 

Selenoprotein T gene-therapy using rAAV8 improves cardiac function and remodeling in rats with heart failure through a selenium-dependent pathway

Paul Mulder, Rouen
 

Co-injection of mesenchymal stem cells with endothelial progenitor cells accelerate muscle recovery in Hind limb ischemia by an endoglin-dependent mechanism

Elisa Rossi, Paris
 

Increased vascular repair function of transplanted human endothelial progenitors through de-repression of bivalent genes

Sylvain Fraineau, Rouen
 

Prolonged elevated levels of resident cardiac progenitor cells do not improve cardiac repair after a myocardial infarction

Amanda Finan, Montpellier
 

Transcriptomic profiling identifies cardiac PW1 cells as a specific population with fibrogenic potential

Jean-Sébastien Hulot, Paris
 

Epicardial progenitors contribute to the fibro-fatty infiltration of the sub-epicardium of human atri

Nadine Suffee, Paris
17:15 - 19:00
Poster
15 - Valvulopathies
Claire Bouleti, Paris
Daniel Grinberg, Lyon
   
 

Impact of CT-ADP point of care assay on 30 days Paravalvular Aortic Regurgitation and bleeding events following Transcatheter Aortic Valve Replacement

Marion Kibler, Strasbourg
 

Endocardial  Cell Heterogenity at the Origin of Valvular Cell Clones

 

B. Fahrat, MARSEILLE
 

Incidence, predictive and prognostic factors of hopitalization for congestiveheart failure after transcatheter aortic valve implantation

 

Maxime Doutriaux, Poissy
 

Effect of high cholesterol diet and vitamin D supplementation in the EGFRwa2/wa2 model of aortic stenosis

Guillaume Avinee, Rouen
 

Late Mitral Restenosis after Percutaneous Commissurotomy: the Predictive Value of Inflammation and Extracellular Matrix Remodeling Biomarkers. 

Marouane Boukhris, Ariana
 

Aortic prosthetic heart valve obstruction caused by pannus : characteristics and diagnostic strategy, about a 71 patients multicentric study 

Rodrigue Garcia, Poitiers
 

IMPACT OF A MULTIDISCIPLINARY APPROACH ON THE MANAGEMENT OF INFECTIOUS ENDOCARDITIS AT THE UNIVERSITY HOSPITAL OF ROUEN

Clément Alarcon, Rouen
 

ASSOCIATION ENTRE LE PHENOTYPE DU TISSU ADIPEUX EPICARDIQUE ET LE DEGRE D’HYPERTROPHIE VENTRICULAIRE GAUCHE DANS LE RETRECISSEMENT AORTIQUE SERRE

Sandro Ninni, Lille
 

Déterminants et pronostic des insuffisances tricuspides sévères

Anne-Sophie Da Silva, Rouen
 

Relationship between Proximal Aorta Morphology and  Progression Rate of Aortic Stenosis

Romain Capoulade, Boston

7 Avril 2017


08:30 - 09:45
Table ronde
TV cathécholergique : un modèle unique de compréhension des arythmiesRythmologie
Salle 300
Philippe Chevalier, Lyon
Estelle Gandjbakhch, Paris
   
 

Quels sont les mécanismes ?

Ana-Maria Gomez, Châtenay-Malabry
 

Evolution de la prise en charge

Antoine Leenhardt, Paris
 

Patient-specific induced pluripotent stem cell-derived cardiomyocytes to model, screen drugs and decipher molecular mechanisms of CPVT1 syndrome

 

 

A novel RYR2 missense mutation causing catecholaminergic polymorphic ventricular tachycardia and numerous sudden deaths.

 

Arrhythmogenic substrate in the healthy right ventricular outflow tract: a common ground for RVOT arrhythmias?

08:30 - 09:45
Table ronde

Session comune avec le Groupe Français d'études sur l'Hémostase et la Thrombose

Les plaquettes au-delà de l'hémostaseVaisseaux
Salle 150
Sandrine Horman, Bruxelles
Jean-Sébastien Hulot, Paris
   
 

Plaquettes et cancer

Cécile Oury, Liège
 

Les plaquettes : des cellules immunitaires ?

Fabrice Cognasse, Saint-Etienne
 

Sustained inhibition of acetyl-CoA carboxylase decreases platelet dense granules secretion and aggregation.

 

ABCC6 dysfunction in the rare disease pseudoxanthoma elasticum is associated to increased platelet activation and prothrombotic state.

08:30 - 09:45
Table ronde
Choc cardiogénique et assistance circulatoireInsuffisance Cardiaque
Salle 200
François Bagate, Créteil
Nathan Mewton, Lyon
   
 

Myocardites fulmi-Nantes

Alain Combes, Paris
 

Des amines à l'assistance cardiaque

B. Levy
 

Pulsatility as modulator of acquired VWF defect in a pig model of continuous-flow ventricular assist device

 

State-of-the-Art of Left Ventricular Assist Device use in France: the ASSIST-ICD registry.

 

Comparaison entre abord percutané et chirurgical de l'ECMO

Arthur Charbonnier, TOURS
08:30 - 09:45
Table ronde
Exercice physique et protection du myocardeMédecine Expérimentale
Salle GH
Claire Arnaud, Grenoble
Olivier Cazorla, Montpellier
   
 

Adaptations cardiaques à l'exercice physique intense

Stéphane Nottin, Avignon
 

L'exercice physique : une solution contre l'hypoxie intermittente

Claire Arnaud, Grenoble
 

Adipose tissue can be trained to counteract metabolic dysfunctions associated with obesity-induced premature aging.

 

Mdm2-FoxOs axis and angio-adaptation exercise-induced suppress brown adipose tissue whitening and activate subcutaneous adipose tissue browning in obese mice

 

Prolonged exhaustive exercise induces diastolic dysfunction with preserved systolic function mediated by oxidative stress.

08:30 - 09:45
Table ronde
Cardiopathies congénitales : modèles animaux vs. modèles cellulairesTransversal
Salle I
Denis Angoulvant, Tours
Laurianne Le Gloan, Nantes
   
 

Modèles animaux d'études des arythmies cardiaques congénitales

Matteo Mangoni, Montpellier
 

Modèles cellulaires d'étude des arythmies cardiaques congénitales

Nathalie Gaborit, Nantes
 

TRPM4 variants associated with long QT syndrome

 

Inhibition of KACh channels by the bee venom peptide tertiapin-Q rescues sino-atrial bradycardia and atrioventricular block in models of congenital sino-atrial dysfunction

 

Tbx1 and Retinoic acid-dependent Tbx5 expression coordinate second heart field progenitor cell addition to alternate cardiac poles

09:45 - 11:30
Session de Posters Commentés & Visite de l'exposition
 
   
09:45 - 11:30
Poster
16 - Athérosclérose, thrombose, hémostase
Chantal Boulanger, Paris
Pierre-Louis Tharaux, Paris
   
 

Use of non-invasive ischemia stress testing in stable coronary artery disease outpatients: analysis of real-life practices (from the CORONOR study)

Pierre Paquet, Lille
 

The role of bile acids and gut microbiota in coronary artery disease: results of the MABAC study in human (Microbiota Atheroma and Bile Acid in Coronary disease).

Caroline Chong-Nguyen, Paris
 

Activation of endothelial autophagy is required for endothelial alignment in flow and atheroprotective signaling

Marouane Kheloufi, Paris
 

Autophagy deficiency in vascular smooth muscle cells leads to unstable atherosclerotic plaque phenotype and enhanced mitophagy markers expression in Apo E-/- mice

 

Coronary and extra-coronary atherosclerotic development is associated with an increase inflammation and thrombin generation markers: a substudy of ACCTHEROMA Clinical Trial

Shakeel Kautbally, Bruxelles
 

Platelet Acetyl-CoA Carboxylase phosphorylation: a potential marker for atherothrombotic coronary artery disease

Shakeel Kautbally, Bruxelles
 

The role of CLEC9a in atherosclerosis development

Yacine Haddad, Bagnolet
 

Role of lipid phosphate phosphatase  and sphingosine-1-phosphate in human aortic endothelial cell function.

 

Nuclear targeting of apelin promotes smooth muscle cell phenotypic transition. Implications in atherosclerosis

Chiraz Chaabane, Genève
 

Sphingosine-1-phosphate redundancy in vascular development, integrity and tone.

09:45 - 11:30
Poster
17 - Ischémie reperfusion, SCA, AVC
Nathan Mewton, Lyon
Denis Angoulvant, Tours
   
 

Major role of HIF-1 in endoplasmique reticulum stress and calcium alterations, leading to increased susceptibility to myocardial ischemia-reperfusion, induced by chronic intermittent hypoxia

Sophie Moulin, Grenoble
 

Opposite effects of mitochondrial fusion and fission deficiencies in the context of myocardial ischemia-reperfusion 

Laura Cellier, Angers
 

Benefit of Mineralocorticoid Receptor antagonism in ischemia-reperfusion induced acute kidney injury: role of vascular smooth muscle Rac1.

Gwennan Andre-Gregoire, Nantes
 

Rôle de la Galectine 3 dans la maladie rénale aigüe.

Magali Genest, Paris
 

Finerenone protects against acute and chronic consequences of renal ischemia/reperfusion

Lionel Lattenist, Paris
 

The TSPO ligand 4’chlorodiazepam inhibits mitochondrial sterol accumulation and protects mitochondrial function in hypercholesterolemic ZDF rats during myocardial ischemia-reperfusion

Julien Musman, Créteil
 

A new and economic device for cellular intermittent hypoxia

Jessica Morand, Grenoble
 

A novel cardioprotection strategy: targeting the ER via the TRANSLOCON, a calcium leak channel.

Ribal Al-Mawla, Lyon
 

Acute coronary artery disease in young adult population of less than 40 years old, clinical and angiographic characteristics

Elodie George, Reims
 

Endothelial microparticles from ACS patients induce premature endothelial cells ageing and thrombogenicity: Role of the Ang II/ATIR/NADPH oxidase-mediated activation of MAPKs and PI3-kinase pathways

Cyril Auger, Strasbourg
 

EPAC1-MEDIATED ER-MITOCHONDRIA INTERACTIONS PROMOTE DELETERIOUS Ca2+ UPTAKE AND CELL DEATH DURING ISCHEMIA/REPERFUSION INJURY.

Loubina Fazal, Toulouse
09:45 - 11:30
Poster
18 - Mitochondries et métabolisme
Cyril Reboul, Avignon
Renée Ventura-Clapier, Châtenay-Malabry
   
 

Sustained inhibition of acetyl-CoA carboxylase decreases platelet dense granules secretion and aggregation.

Sophie Lepropre, Bruxelles
 

AMPKα1 participates in the regulation of thrombin-induced phosphatidylserine exposure in platelets through acetyl-CoA carboxylase phosphorylation.

Sophie Lepropre, Bruxelles
 

Beneficial effects of an orallyactive carbon monoxide-releasing molecule (CORM-401) on high fat diet-induced obesity in mice

Laura Braud, Créteil
 

Changes of mitochondrial dynamic evoked by circulating exosomes are associated to endothelial dysfunction in metabolic syndrome.

Marine Malloci, Angers
 

High intensity aerobic exercise training improves chronic intermittent hypoxia-induced insulin resistance without basal autophagy modulation

Marion Pauly, Grenoble
 

Increased ROS generation involves mitochondria in MR-overexpressing adipocytes – impact on vascular function.

 

Adipose tissue can be trained to counteract metabolic dysfunctions associated with obesity-induced premature aging.

Maria Pini, Creteil
 

Protective role of ischemic conditioning procedures against skeletal muscle ischemia-reperfusion injury via improving in vivo energy metabolism and mitochondrial function

Dominique Detaille, Bordeaux
 

Modulation of Mitochondrial Adenine Nucleotide Translocase (ANT) regulation with ageing

Philippe Diolez, Bordeaux
09:45 - 11:30
Poster
19 - Diabètes et lipides
Luc Bertrand, Bruxelles
Xavier Prieur, Nantes
   
 

Treshold value of admission glycemia predictive of higher in-hospital mortality during STEMI in non-diabetic patients

 

Transgenerational impact of maternal diabetes on vascular function in F2 rat's offspring

Cyrielle Payen, Angers
 

Intolerance to glucose and abdominal obesity in a diet-induced metabolic syndrome model were associated with modification of cardiac morphology and impaired myocardial function.

Natacha Fourny, Marseille
 

Impact of obstructive sleep apnea on the endothelial function in patients with type 2 diabetes

Carmen Martinez, Angers
 

Proteomic profiling of extracellular vesicles derived from adipocytes reveals the presence of key metabolic proteins involved in the development of cardiovascular diseases associated with obesity

Maëva Durcin, Angers
 

CARACTÉRISATION PHÉNOTYPIQUE DU TISSU ADIPEUX ÉPICARDIQUE EN CAS DE SYNDROME METABOLIQUE. IMPACT DE CE PHENOTYPE SUR LE PRONOSTIC DE LA CHIRURGIE DE PONTAGE AORTO-CORONAIRE

Cédric Klein, Lille
 

Chronic AICAR treatment improves stimulated glucose transport in cardiomyocytes exposed to free fatty acids

Christophe Montessuit, Genève
 

An anthocyanin-rich black currant extract prevents high glucose-induced senescence and dysfunction in cultured coronary artery endothelial cells

Cyril Auger, Strasbourg
 

GLP-1 and angiogenesis : Safety of T2 diabetes treatment ?

Samaher Besbes, Paris
09:45 - 11:30
Poster
20 - Stress oxydant et NO
Claire Arnaud, Grenoble
Catherine Vergely-Vandriesse, Dijon
   
 

Roles and Mechanisms of Action of Aldehydes Produced by Monoamine Oxidase-A in Cardiomyocyte Death and Heart Failure

Yohan Santin, Toulouse
 

Homéostasie du zinc et atteintes myocardiques liées au stress oxydant

Jessica Morand, Grenoble
 

Effet de l’exercice sur la translocation de la eNOS vers les mitochondries sub-sarcolemmales.

Doria Boulghobra, Avignon
 

EPR spectroscopy quantification of HbNO as an index of vascular nitric oxide bioavailability in vivo.

Flavia Dei Zotti, Bruxelles
 

Monoamine oxidases as molecular players of cardiac senescence

Nicola Manzella, Toulouse
 

Exercice physique et remodelage du Tissu Adipeux Périvasculaire chez des rats obèses : quelles conséquences sur la fonction vasculaire ?

Cindy Meziat, Avignon
 

Effect of sildenafil on cardiovascular reactivity and gut microbiota in a metabolic syndrome model in spontaneously hypertensive rats

Yosra Doghri, Nantes
 

Chronic oral intake of EPA:DHA 6:1 improves both the NO and EDH components of ageing-related endothelial dysfunction and vascular oxidative stress in rats

Muhammad Akmal Farooq, Strasbourg
 

Implication de la superoxyde dismutase 2 dans la régulation du stress oxydant lors de l’insuffisance cardiaque.

Emilie Dubois-Deruy, Lille
 

Deficiency in Estrogen Receptor alpha membrane signaling is responsible for premature vascular dysfunction in response to flow shear stress in male mice

Julie Favre, Angers
 

Impact of high fat diet on oxidative stress and cardiac structure of pre-pubertal female and male rabbits

09:45 - 11:30
Poster
21 - Angiogenèse et microcirculation
Stéphane Germain, Paris
Laurent Loufrani, Angers
   
 

AMP-activated protein kinase α1 controls cytosolic calcium concentration and induces calcium sensitization in resistance arteries

Thomas Metzinger, Bruxelles
 

Etude des jonctions endothéliales dans les vaisseaux tumoraux cérébraux

 

Quentin Roux, Nantes
 

Preclinical study of a new Apelin receptor antagonist against glioblastoma.

Gwennan Andre-Gregoire, Nantes
 

Mdm2-FoxOs axis and angio-adaptation exercise-induced suppress brown adipose tissue whitening and activate subcutaneous adipose tissue browning in obese mice

Thomas Loustau, Avignon
 

Avoiding non-specific vasodilatory effects in transdermal iontophoresis when assessing cutaneous microvascular function

Jordan Loader, Avignon
 

Notch3 modulates the cardiovascular adaptation to volume-overload

Hélène Ragot, Paris
 

The Brain Natriuretic Peptide Improves Cardiac Function After Myocardial Infarction Through Vascular Regeneration

Na Li, Lausanne
 

Human aortic valvular interstitial cells: evidence of vasculogenic potential during aortic valve stenosis

Nicolas Gendron, Paris
 

RENAL SYMPATHETIC DENERVATION IMPROVES SYSTEMIC MICROVASCULAR ENDOTHELIAL FUNCTION IN PATIENTS WITH RESISTANT HYPERTENSION

Alessandro Nascimento, Rio De Janeiro
 

Dhh-induced autocrine signaling in endothelial cells is critical for endothelium integrity

Marie-Ange Renault, Bordeaux
 

Apelin is involved in the maintenance of lymphatic barrier integrity in ischemic heart disease

Barbara Garmy-Susini, Toulouse
 

PPARα carried by microparticles restores the failed differentiation and functionality of bone marrow-derived cells induced by high-fat diet

Luisa Vergori, Angers
09:45 - 11:30
Poster
22 - Electrophysiologie
Jérémy Fauconnier, Montpellier
Thierry Le Tourneau, Nantes
   
 

Rad GTPase as a new potential actor in Brugada syndrome

                                 Electrophysiology

Nadjet Belbachir, Nantes
 

Risk of myocardial infarction and death in patients with atrial  fibrillation treated with dabigatran or vitamin K antagonists

Walid Darwiche, Tours
 

BLEEDING RISK IN PATIENTS TREATED WITH DABIGATRAN OR VITAMIN K

ANTAGONIST FOR ATRIAL FIBRILLATION : A META ANALYSIS OF

ADJUSTED ANALYSIS IN ROUTINE PRACTICE SETTINGS

Walid Darwiche, Tours
 

Brugada syndrome in women

Pauline Berthome, Nantes
 

Brugada syndrome in elderly patients

 

Early repolarization syndrome is not related with ventricular arrhythmias in Brugada patients

Romain Tixier, Bordeaux
 

QRS fragmentation is highly related with ventricular arrhythmias in Brugada patients

Romain Tixier, Bordeaux
 

Rotor in atrial fibrillation and impact of ablation

Caroline Cros, Bordeaux
 

C-TERMINAL PHOSPHORYLATION OF NaV1.5 CHANNELS IMPAIRS FGF13-DEPENDENT INACTIVATION: POTENTIAL IMPACT IN HEART FAILURE

Maxime Lorenzini, Nantes
09:45 - 11:30
Poster
23 - Electrophysiologie
Dominique Babuty, Tours
Grégoire Vandecasteele, Châtenay-Malabry
   
 

arrhythmia in pregnant women with decompensated heart failure 

 

La relation entre la durée du QT et l’intervalle RR chez la souris : QT ou QTc ? 

Julien Roussel, montpellier
 

Atrial fibrillation is associated with hypermethylation in human left atrium and treatment with decitabine reduces atrial tachyarrhythmias in spontaneously hypertensive rats

Rosa Doñate Puertas, LYON
 

Diagnosis accuracy of provocative tests in concealed Long QT Syndrome.

Pauline Etienne, Nantes
 

High arrhythmogenic potential of calcium waves in rat isolated pulmonary vein cardiomyocytes

Côme Pasqualin, Tours
 

Specific tissue structure of the right ventricular outflow tract as a substrate for arrhythmias

Virginie Dubes, Bordeaux
 

TRPM4 variants associated with long QT syndrome

Thomas Hof, Bordeaux
 

Outcome after aborted cardiac arrest related to ventricular arrhythmias

Benjamin Stordeur, Poitiers
 

Arrhythmogenic substrate in the healthy right ventricular outflow tract: a common ground for RVOT arrhythmias?

David Benoist, Bordeaux
 

Risk stratification of arrhythmia and death in ARVC

Jean-Baptiste Gourraud, Nantes
09:45 - 11:30
Poster
24 - Electrophysiologie
Vincent Probst, Nantes
Ana-Maria Gomez, Châtenay-Malabry
   
 

PAR1 contribution in acute electrophysiological properties of oral anticoagulants in rabbit pulmonary vein sleeve preparations

Jonaz Font, Caen
 

hERG S4-S5 linker acts as a voltage-dependent ligand that binds to the activation gate and locks it in a closed state

Olfat Malak, Nantes
 

Hamamy syndrome: Deciphering the role of IRX5 transcription factor in the regulation of human cardiac electrical conduction

Zeina Reda Al Sayed, Nantes
 

Modulation of myocardial NOX2 activity regulates atrial fibrillation susceptibility

Alice Recalde, Bordeaux
 

Patient-specific induced pluripotent stem cell-derived cardiomyocytes to model, screen drugs and decipher molecular mechanisms of CPVT1 syndrome

 

Yvonne Sleiman, Montpellier
 

A novel RYR2 missense mutation causing catecholaminergic polymorphic ventricular tachycardia and numerous sudden deaths.

Malorie Blancard, Paris
 

ATRIAL NATRIURETIC PEPTIDE REGULATES THE ADIPOGENIC DIFFERENTIATION OF HUMAN ATRIAL EPICARDIAL PROGENITORS 

Nadine Suffee, Paris
 

Characterization of new voltage sensitive dyes (VSDs) in cardiac tissue

Rokhaya Faye, Bordeaux
 

Left ventricular reverse remodeling and super responders after Cardiac Resynchronization Therapy.

 

Cardiotoxicity of free and encapsulated artemether in cardiomyocytes: contractility and transient calcium analysis.

09:45 - 11:30
Poster
25 - Insuffisance cardiaque et cardiomyopathies + Réadaptation, exercice, prévention
Alain Lacampagne, Montpellier
Mathias Mericskay, Paris
   
 

Impact of four weeks intermittent hypoxia on calcium handling proteins in a rat model of post-ischemic heart failure.

Maximin Détrait, Grenoble
 

T cells contribute to cardiac lymphatic remodeling post-MI

Mahmoud Houssari, Rouen
 

Improved metabolic syndrome-related right and left ventricular dysfunction by the dual ETA-ETB receptor antagonist macitentan

Marianne Lachaux, Rouen
 

Characterization of IH-induced cardiac remodeling and contractile dysfunction in a rat model of post-ischemic heart failure

Guillaume Bourdier, Grenoble
 

Altered iron regulation after extended acute reperfused ST-segment-elevation myocardial infarction

Mansour Mostefa-Kara, Paris
 

ROLE OF NGAL IN THE CARDIAC REMODELING ASSOCIATED WITH MYOCARDIAL INFARCTION

Ernesto Martinez-Martinez, Paris
 

An intravenous bolus of EPA:DHA 6:1 protects against myocardial ischemia-reperfusion-induced shock

Mélanie Burban, Nantes
 

La Clusterine : expression et fonction dans le remodelage ventriculaire gauche

Annie Turkieh, Lille
 

Intra-cardiac release of extracellular vesicles governs infiltrating monocyte activation following myocardial infarction

Chantal Boulanger, Paris
 

Hospitalization for heart failure in stable coronary artery disease outpatients: determinants, role of interim myocardial infarction, and prognosis

09:45 - 11:30
Poster
26 - Insuffisance cardiaque et cardiomyopathies + Réadaptation, exercice, prévention
Jean-Sébastien Hulot, Paris
Yves Juilliere, Nancy
   
 

Lineage analysis of ventricular trabeculae to decipher the role of Nkx2-5 in conduction system development

Caroline Choquet, Marseille
 

Bcl11b, a transcription factor: its role in transcriptional regulation of cardiac hypertrophy.

Marie Thérèse Daher, Paris
 

Temporal deletions of Nkx2-5 induce hypertrabeculation and progressive conduction defects and heart failure

Caroline Choquet, Marseille
 

Left ventricular dysfunction and heart failure manifestations in Duchenne muscular dystrophy
 

 

Association between Mutation Size and Cardiac Involvement in Myotonic Dystrophy Type 1: an Analysis of the DM1-Heart Registry

Caroline Chong-Nguyen, Paris
 

Characterization of progressive cardiac dysfunction in dystrophin deficient DMDmdx rat: a new model for Duchenne Muscular Dystrophy.

Emeline Amossé, Nantes
 

Epigenetic role of Carabin during cardiac hypertrophy

Roberto Pane, Toulouse
 

Left ventricular longitudinal strain predicts cardiovascular events in type 1 myotonic dystrophy.

Nicolas Bidegain, Poitiers
 

Shared gene expression profile between aging and diseased hearts in man

Marja Steenman, Nantes
 

Exome-wide Association Study Reveals Novel Susceptibility Genes to Sporadic Dilated Cardiomyopathy.

Eric Villard, Paris
09:45 - 11:30
Poster
27 - Hypertension, remodelage et rigidité artériel, HTAP
Nathalie Rosenblatt-Velin, Lausanne
Vincent Sauzeau, Nantes
   
 

Nuclear actions of Estrogen Receptor Alpha are protective against angiotensin II induced hypertension in mice

Emmanuel Guivarc'h, Angers
 

Antihypertensive effect of refined olive oil enriched with hydroxytyrosol in a mice model of type 2 diabetes mellitus: implication of smooth muscle cells relaxation

Julien Peyrol, Avignon
 

Neutrophil and Thrombospondin-1 implications in flow-mediated remodeling in the microcirculation.

Tristan Champin, Angers
 

TRPV4-induced structural changes in the adventitia of intrapulmonary artery.

Laure-Anne Cussac, Bordeaux
 

Cardioprotective effect of ipriflavone in female spontaneously hypertensive rats submitted to the left coronary ligature

Thales Martins, Montpellier
 

The role of integrin alpha v TGF-b pathway in vascular fibrosis

Zhenlin Li, Paris
 

Nav1.5 channel is expressed in lungs: localization and functional involvements.

Andréa Fonteneau, Nantes
 

Non catalytic function of PI3Kg on smooth muscle cells proliferation: a novel therapeutic strategy to prevent arterial remodeling through cAMP modulation.

 

Smooth muscle Rac1 contributes to pulmonary hypertension

Florian Dilasser, Nantes
 

Clinical phenotypes and outcomes of heritable and sporadic pulmonary veno-occlusive disease: A population-based study.

David Montani, Le Kremlin Bicetre
 

Regulation of Pulmonary Vascular PW1+ Progenitor Cells Recruitment during Early Chronic Hypoxia-Induced Vessel Neomuscularization

Sophie Nadaud, Paris
 

RhoA and Rac1 crosstalk in arterial remodeling

Nathalie Vaillant, Nantes
 

Erythropoietin recapitulates hemodynamic features of hypoxia-induced pulmonary hypertension in mice

Ghina Bouabout, Strasbourg
09:45 - 11:30
Poster
28 - Imagerie cardiovasculaire et chirurgie cardiaque, cardiopathies congénitales
Francesca Rochais, Marseille
Renaud Tissier, Maisons-Alfort
   
 

Tbx1 and Retinoic acid-dependent Tbx5 expression coordinate second heart field progenitor cell addition to alternate cardiac poles

Christopher De Bono, Marseille
 

Dobutamine stress echocardiography unmasks early left ventricular dysfunction in asymptomatic metabolic syndrome patients: preliminary results.

Clothilde Philouze, Avignon
 

Speckle tracking echocardiography in systemic sclerosis: A useful method for detection of myocardial involvement

 

A convenient plug-in suite for cardiomyocyte image and video analysis with ImageJ

Côme Pasqualin, Tours
 

Inhibition of KACh channels by the bee venom peptide tertiapin-Q rescues sino-atrial bradycardia and atrioventricular block in models of congenital sino-atrial dysfunction

Antony Chung You Chong, Montpellier
 

Critical pulmonary valve stenosis of the newborn: early and long term outcome

 

Real life versus score-predicted mortality in patients presented to the Heart Team

Léa Cacoub, Paris
 

La diminution de la cadence d’acquisition à 3,75 images/seconde en fluoroscopie permet-elle la réduction de la dose de rayon délivrée au patient en angiographie coronaire

Benoit Le Rest, Brest
 

IRM cardiaque chez les patients transplantés : Intérêt diagnostique de la cartographie T2 et de la quantification du volume extra-cellulaire myocardique dans la détection du rejet de greffe

Clémence Pantaléon, Tours
 

TRANSTHORACIC ECHOCARDIOGRAPHY TO QUANTIFY PULMONARY VASCULAR RESISTANCE IN PATIENTS WITH SYSTEMIC SCLEROSIS

Sophie Billet, Toulouse
 

Implantation of a bioprosthetic total artificial heart induces a profile of acquired hemocompatibility with recellularization of its blood-contacting membranes

David Smadja, Paris
 

Quantitative analysis of 3D imaging of mouse coronary vasculature

Etienne Roux, Bordeaux
09:45 - 11:30
Poster
29 - Valvulopathies
Claire Bouleti, Paris
Jean-Jacques Schott, Nantes
   
 

Impact on Discharge of Non Cardiovascular Complications after Trans-catheter Aortic Valve Implantation.

Antoine Noel, Brest
 

Thoracic aorta calcifications and TAVI : evaluation of automatic measurements and prognostic value on the cohort of Rouen.

Marion Dupré, Rouen
 

 Impact of Pulmonary Pressure on Long Term Outcome in Patients with Aortic Stenosis 

Yohann Bohbot, Amiens
 

Determinants of left atrial volume index in patients with aortic stenosis. A multicentre pilot study. 

Yohann Bohbot, Amiens
 

Infective endocarditis complicated by heart failure

 

DEVENIR MATERNEL APRES DILATATION MITRALE PERCUTANEE PENDANT LA GROSSESSE : RESULTATS A 20 ANS

 

Impact of screening by coronary angiography and revascularization by angioplasty of significant coronary lesions before transcatheter aortic valve implantation.

Safwane El Hatimi, Le-Kremlin-Bicêtre
 

Neurologic Manifestations of Infective Endocarditis : A 10-Years Experience in U.Hospital Ibn Rochd

Karim Hafdi, Casablanca
 

Perioperative complications in transcathter aortic valve implantation, in patients with pre existing atrial fibrillation : vitamine K antagonist treatment versus new direct oral anticoagulant

Camille Caussin, Rouen
 

Mimicking The Physiopathology Of Aortic Valve Stenosis In Vitro: Which Osteogenic Media On Human Valvular Interstitial Cells?

Yoann Sottejeau, Lille
 

Identification of a sub-population of neural crest cells involved in the formation of the aortic valve

Stéphane Zaffran, Marseille
11:30 - 12:45
Table ronde
Arythmies et prolapsus valvulaire mitral (PVM)Rythmologie
Salle 300
Thierry Le Tourneau, Nantes
Philippe Mabo, Rennes
   
 

Aspects génétiques et biologiques du PVM

Jean-Jacques Schott, Nantes
 

Du PVM à la mort subite : mécanisme et traitements ?

Jérôme Hourdain, Marseille
 

Endocardial  Cell Heterogenity at the Origin of Valvular Cell Clones

 

 

Outcome after aborted cardiac arrest related to ventricular arrhythmias

 

Identification of a sub-population of neural crest cells involved in the formation of the aortic valve

11:30 - 12:45
Table ronde
Biomécanique : le vaisseau n'est pas un long fleuve tranquilleVaisseaux
Salle 150
Laurent Loufrani, Angers
Vincent Sauzeau, Nantes
   
 

Canaux piezo : nouveaux acteurs dans le remodelage artériel ?

Eric Honore, Nice
 

Implication de la membrane basale dans la mécano transduction endothéliale

Laurent Muller, Paris
 

Endothelial ATG5 is required for endothelial flow sensing and angiogenesis 

 

The role of integrin alpha v TGF-b pathway in vascular fibrosis

Zhenlin Li, Paris
 

Development of 3D engineered heart tissue (EHT) technology for the study of cardiac contractile dysfunction

11:30 - 12:45
Table ronde
Transplantation cardiaqueInsuffisance Cardiaque
Salle 200
Clémence Pantaléon, Tours
Jean-Noël Trochu, Nantes
   
 

La recherche clinique en transplantation cardiaque en France

Jean-Noël Trochu, Nantes
 

Mécanismes de la maladie vasculaire du greffon

J. Guihaire
 

La stimulation de P2Y11R réduit les lésions de reperfusion dans une lignée de cardiomyocytes humains et améliore la survie du greffon dans un modèle murin d'allogreffe cardiaque hétérotopique

 

IRM cardiaque chez les patients transplantés : Intérêt diagnostique de la cartographie T2 et de la quantification du volume extra-cellulaire myocardique dans la détection du rejet de greffe

 

Implantation of a bioprosthetic total artificial heart induces a profile of acquired hemocompatibility with recellularization of its blood-contacting membranes

11:30 - 12:45
Table ronde
Pathologie cardiaque mitochondriale : acquise ou innnée ?Médecine Expérimentale
Salle GH
Jérémy Fauconnier, Montpellier
Renée Ventura-Clapier, Châtenay-Malabry
   
 

Cardiomyopathie diabétique : une pathologie mitochondriale acquise

David Montaigne, Lille
 

Atteinte cardiaque des pathologies mitochondriales d'origine génétique

Anne Lombes, Paris
 

Cardiac mitochondrial complex I dysfunction is associated with an increase in sarcoplasmic reticulum leak in a Duchenne muscular dystrophy. 

 

Mitochondrial biogenesis is driven by protein translation during ischemia and reperfusion

 

EPAC1-CaMKII pathway targets mitochondrial IDH2 during cardiac ischemia

11:30 - 12:45
Session d'experts
La médecine numériqueTransversal
Salle I
Aymeric Menet, Lille
Vincent Probst, Nantes
   
 

Méthodes, traitement du signal et modélisation physiologique 

Alfredo Hernandez, Rennes
 

Banques de données évolutives ou les banques de données intelligentes

Vincent Probst, Nantes
 

La machine learning

Pierre-Antoine Gourraud, Nantes
13:00 - 14:00
Déjeuner-Débat

Amgen

Inhibition de PCSK9 : prise en charge du patient à haut-risque cardiovasculaire à la lumière des nouvelles données cliniquesVaisseaux
Salle 150
Michel Krempf, Nantes
François Paillard, Rennes
   
 

Inhibition de PCSK9 : de l’identification d’un gène à l’application clinique

Bertrand Cariou, Nantes
 

Réduire la plaque coronaire sous traitement hypolipémiant

Denis Angoulvant, Tours
14:00 - 14:30
Pause-café - Visite de l'exposition
 
   
08:30 - 19:00
Atelier scientifique
Atelier scientifique BayerMédecine Expérimentale
Salle GH
   
 

AODs : Quelles avancées thérapeutiques ?

Christophe Leclercq, Rennes
14:30 - 15:00
Conférence Jacques Puel
 
Auditorium 450
Jean-Yves Le Heuzey, Paris
   
 

De la génétique à la médecine 4P

Hervé Le Marec, Nantes
15:15 - 16:30
Table ronde
Imagerie en rythmologieRythmologie
Salle 300
Jean-Baptiste Gourraud, Nantes
Philippe Mabo, Rennes
   
 

Système de cartographie en 3D

Jean-Marc Sellal, Nancy
 

Intégration de l'imagerie en électrophysiologie et en resynchronisation cardiaque

Hubert Cochet, Bordeaux
 

Non-invasive multimodal imaging techniques for in vivo characterization of electrical dyssynchrony in large animal models: feasibility study

 

Intérêt pronostique du volume et de la fraction d'éjection de l'oreillette gauche, mesurées au scanner multicoupe, sur le succès d'ablation de la fibrillation auriculaire

 

Specific tissue structure of the right ventricular outflow tract as a substrate for arrhythmias

15:15 - 16:30
Table ronde
MicrocirculationVaisseaux
Salle 150
Julie Gavard, Nantes
Pierre-Louis Tharaux, Paris
   
 

Microcirculation, hypertension, inflammation, mitochondrie : un cocktail délétère !

Laurent Loufrani, Angers
 

Perivascular recruitment of mesenchymal stem cells in vascularized 3D hydrogel

 

The Endothelin B Receptor Plays a Crucial Role for the Recruitment of Neutrophils to the Endothelium in Sickle Cell Disease

 

Dhh-induced autocrine signaling in endothelial cells is critical for endothelium integrity

 

Abrogating Frizzled7 in endothelial cell protects against the development of pathological angiogenesis during proliferative retinopathy

15:15 - 16:30
Controverse
L'insulino-résistance : phénomène délétère ou protection pour le coeur diabétique ?Insuffisance Cardiaque
Salle 200
Luc Bertrand, Bruxelles
Catherine Vergely-Vandriesse, Dijon
   
 

L'insulino-résistance cardiaque : un mécanisme protecteur

Christophe Beauloye, Bruxelles
 

L'insulino-résistance cardiaque : un mécanisme délétère

Cyril Reboul, Avignon
15:15 - 16:30
Quizz
Quizz du Printemps de la CardiologieTransversal
Salle I
Julien Barc, Nantes
Théo Pezel, Paris
Jérôme Thireau, Montpellier
   
15:15 - 16:30
Table ronde
Régulation épigénétique du myocardeMédecine Expérimentale
Salle GH
Frank Lezoualc'h, Toulouse
Florence Pinet, Lille
   
 

Longs ARNs non-codants en pathologie cardiaque

Thierry Pedrazzini, Lausanne
 

Impact de l'architecture de la chromatine dans l'homéostasie cardiaque

Thomas Moore-Morris, Marseille
 

Bcl11b, a transcription factor: its role in transcriptional regulation of cardiac hypertrophy.

 

Implication des exosomes dans le transport et le rôle des miR-21-5p et 222-3p lors du remodelage ventriculaire gauche post-infarctus.

 

Epigenetic role of Carabin during cardiac hypertrophy

 

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